Is CBD Worth It? Here’s What You Need to Know Before Trying It

By now, you’ve probably heard someone mention CBD, especially if you live with a chronic condition like pain or anxiety. In fact, according to a Healthline survey conducted in February 2023, 25% of adults in the US have tried or are interested in trying CBD products. If you’re looking to try CBD but aren’t sure where to start, this guide can help answer your questions and clear up some of the common misconceptions surrounding CBD and its uses.

Table of Contents

Key Takeaways

  • CBD, found in cannabis along with THC, doesn’t cause a high and may help manage certain health conditions, improve mood, and reduce pain.
  • It’s important to speak with a qualified healthcare professional before trying CBD, especially if you have underlying health conditions or are taking other medications.
  • CBD comes in various forms, including oils, tinctures, edibles, and topicals, each with different benefits and uses.
  • Potential side effects of CBD include nausea, irritability, and sleepiness. It’s also important to be aware of potential drug interactions.
  • More research is needed to fully understand the benefits and risks of CBD, and ongoing studies are looking into its potential applications for various health issues.

Understanding Cannabidiol: What is CBD?

Understanding Cannabidiol What is CBD
Understanding Cannabidiol What is CBD

Chemical Composition of CBD

Cannabidiol (CBD) is one of many active compounds found in cannabis plants, including Cannabis sativa, Cannabis indica, and Cannabis ruderalis. Unlike its counterpart tetrahydrocannabinol (THC), CBD is non-psychoactive, meaning it does not cause a “high.” CBD interacts with the body’s endocannabinoid system to help regulate various physiological processes such as anxiety, mood, and appetite.

Sources of CBD

CBD is primarily extracted from the hemp plant (Cannabis ruderalis), which typically contains higher quantities of CBD compared to other cannabis species. It can also be derived from marijuana, but hemp-derived CBD is more commonly used due to its legal status and lower THC content. Additionally, CBD can be synthesized in laboratories.

Legality of CBD

The legal status of CBD varies widely. In the United States, CBD derived from industrial hemp is legal in most states, provided it contains less than 0.3% THC. However, it is not considered a dietary supplement by the FDA. Prescription forms of CBD, such as Epidiolex, are approved for specific medical conditions. It is crucial to consult local regulations to understand the legal landscape of CBD in your area.

The growing popularity of CBD has led to its inclusion in a variety of products, from oils and tinctures to edibles and even CBD for pets. Despite its widespread use, it is essential to be aware of the legal and safety considerations associated with CBD products.

The Mechanism of Action: How Does CBD Work?

Cannabidiol (CBD) interacts with the body’s endocannabinoid system (ECS), which plays a crucial role in regulating various physiological processes. The ECS consists of cannabinoid receptors, primarily CB1 and CB2, which are found throughout the body. CBD may activate or block these receptors, influencing functions such as sleep, mood, and appetite.

Interaction with the Endocannabinoid System

CBD’s interaction with the ECS is complex. It does not bind directly to CB1 or CB2 receptors like tetrahydrocannabinol (THC) does. Instead, it modulates the receptors’ activity, potentially enhancing the body’s natural endocannabinoids’ effects. This modulation can lead to various therapeutic outcomes, including pain relief and reduced inflammation.

Effects on Neurotransmitters

CBD also impacts neurotransmitter systems beyond the ECS. It may interact with serotonin receptors, which are involved in mood regulation, and opioid receptors, which play a role in pain control. Additionally, CBD may influence glycine receptors, which are crucial for mood control. These interactions suggest that CBD has a broad spectrum of potential effects on mental and physical health.

Influence on Inflammation

One of the significant ways CBD exerts its effects is through its anti-inflammatory properties. By targeting endocannabinoid receptor activity and interacting with neurotransmitters, CBD may help reduce chronic pain and inflammation. This makes it a promising candidate for managing conditions like arthritis and fibromyalgia.

Understanding the mechanism of action of CBD is essential for appreciating its potential therapeutic benefits and risks. Ongoing research continues to uncover the complexities of how CBD works within the body.

Comparing CBD with Other Cannabinoids

Differences Between CBD and THC

Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two of the most well-known cannabinoids found in the cannabis plant. While both compounds interact with the body’s endocannabinoid system, they have distinct effects. CBD does not cause a high, unlike THC, which is psychoactive. This fundamental difference makes CBD a more appealing option for those seeking therapeutic benefits without the mind-altering effects associated with THC.

CBD vs. CBN: What Sets Them Apart?

Cannabinol (CBN) is another cannabinoid that is often compared to CBD. While both CBD and CBN are derived from the cannabis plant, they have different origins and effects. CBN is typically found in aged cannabis and is a result of THC degradation. Unlike CBD, CBN is mildly psychoactive, though not to the extent of THC. Additionally, CBN is often associated with sedative effects, making it potentially useful for sleep disorders.

Synergistic Effects of Cannabinoids

The interaction between various cannabinoids can lead to what is known as the entourage effect. This phenomenon suggests that cannabinoids may work better together than in isolation. For example, combining CBD with small amounts of THC can enhance the therapeutic effects of both compounds. This synergy is also observed with other cannabinoids like CBN and cannabigerol (CBG), potentially offering a broader range of benefits.

The entourage effect underscores the importance of using full-spectrum or broad-spectrum CBD products, which contain multiple cannabinoids, for a more comprehensive therapeutic experience.

In specialized applications, such as CBD for horses, understanding these differences and synergistic effects can be crucial for effective treatment.

Potential Health Benefits of CBD

Potential Health Benefits of CBD
Potential Health Benefits of CBD

CBD for Pain Management

CBD has been extensively studied for its potential in pain management. Research indicates that CBD may help alleviate chronic pain by interacting with the endocannabinoid system and reducing inflammation. This makes it a promising alternative for individuals seeking non-opioid pain relief options.

CBD and Anxiety Reduction

CBD is also being explored for its role in reducing anxiety. Studies suggest that CBD can influence the brain’s receptors for serotonin, a neurotransmitter that regulates mood and social behavior. This interaction may help reduce symptoms of anxiety disorders, making CBD a potential option for those seeking natural remedies.

CBD’s Role in Sleep Improvement

Another area where CBD shows promise is in improving sleep quality. Preliminary research suggests that CBD may help with insomnia and other sleep disorders by addressing the root causes, such as anxiety and pain. This could be particularly beneficial for individuals struggling with sleep issues.

While these findings are encouraging, more research into the potential benefits of CBD treatment is needed to fully understand its efficacy and safety.

Risks and Side Effects of CBD Usage

Common Side Effects

CBD use also carries some risks. Though it’s often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue. The most common side effects of CBD oil that were reported include the following:

  • Change in appetite
  • Drowsiness or fatigue
  • Diarrhea
  • Change in liver enzymes

Potential Drug Interactions

CBD can also interact with other medications you’re taking, such as blood thinners. It’s important not to mix CBD with alcohol or any medications that have a sedative effect. Watch for any changes in your mood or thinking patterns.

Long-term Safety Concerns

More research is needed to truly understand the potential benefits of using CBD as a treatment for mental and physical health conditions. Severe side effects have been noted in people with treatment-resistant epilepsy. These include:

  • Anxiety
  • Impaired cognition
  • Psychosis

Research on mice suggests possible harm to the male reproductive system. Another concern comes from human trials for Epidiolex, which found that high doses of CBD were associated with signs of liver damage in a small number of study participants. The liver risks increased when CBD was combined with certain other medications.

Forms of CBD Products Available

CBD is available in several different forms, allowing individuals to tailor their method of use to their specific needs. Here are the most common forms of CBD.

CBD Oils and Tinctures

These liquids, usually oils, are infused with CBD and placed under the tongue with a dropper. The oral mucosa is full of tiny capillaries that absorb the compounds quickly. Oils and tinctures may be a good choice for people who can’t take pills or capsules.

Edible CBD Products

CBD is also available in various edible forms, such as gummies, lollipops, and even high-end sports bras. These products are often chosen for their convenience and ease of use. They are particularly popular among those who prefer not to inhale or apply CBD topically.

Topical CBD Applications

Topical CBD products include lotions, creams, and balms that are applied directly to the skin. These are often used for localized relief of pain, inflammation, or skin conditions. The range of CBD products now available is as broad as the health claims these products are marketed with.

Important Note: If you live in a state that hasn’t yet legalized medical cannabis or these products are unavailable, you can still benefit from products containing industrial hemp-derived CBD. We suggest checking your state’s laws regarding CBD oil.

Guidelines for CBD Dosage

Guidelines for CBD Dosage
Guidelines for CBD Dosage

Factors Influencing Dosage

Determining the appropriate dosage of CBD can be complex, as it depends on various factors including body weight, metabolism, and the specific condition being treated. Individual responses to CBD can vary significantly. It is crucial to consider these factors to tailor the dosage to individual needs.

Starting Low and Going Slow

A common recommendation is to start with a low dose and gradually increase it. This approach helps in understanding how one’s body reacts to CBD. For instance, starting with a small amount of CBD oil or CBD gummies and monitoring the effects can be a prudent strategy. This method minimizes the risk of adverse effects and helps in finding the optimal dose.

Consulting Healthcare Professionals

Before starting CBD, it is advisable to consult with a healthcare provider, especially for individuals with underlying health conditions or those taking other medications. A healthcare professional can provide personalized advice and ensure that the CBD dosage is appropriate and safe.

Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs.

Evaluating the Quality of CBD Products

Importance of Third-Party Testing

Ensuring the quality of CBD products is paramount, given the prevalence of low-quality options in the marketplace. One of the most reliable ways to verify product quality is through third-party testing. Third-party testing involves independent laboratories assessing the product for its CBD and THC levels, as well as potential contaminants such as pesticides and heavy metals. Consumers should look for products that come with a Certificate of Analysis (COA), which provides detailed information about the test results. Brands like NuLeaf Naturals and Bluebird Botanicals are known for offering batch reports on their websites, ensuring transparency and trust.

Understanding Product Labels

Reading and understanding product labels is crucial for making informed decisions. Labels should clearly state the amount of CBD per serving, the total amount of CBD in the product, and any other cannabinoids present. Additionally, labels should include information about the extraction method used and whether the product is full-spectrum, broad-spectrum, or an isolate. Full-spectrum products contain a range of cannabinoids and terpenes, which may offer synergistic benefits, while isolates contain only CBD.

Identifying Reputable Brands

Choosing reputable brands is essential for obtaining high-quality CBD products. Reputable brands often adhere to current Good Manufacturing Practices (cGMP) and provide transparency about their sourcing and manufacturing processes. Consumers should research brands to ensure they have a history of positive reviews and reliable customer service. Additionally, reputable brands will often have their products tested by accredited third-party laboratories and make these results readily available to consumers.

“The CBD administered in research trials is not comparable to what you get at the gas station or online. You can’t necessarily even call some of the unregulated products CBD.” – Shanna Babalonis, PhD, University of Kentucky College of Medicine

Legal and Regulatory Aspects of CBD

Federal vs. State Laws

CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal — that would be like making oranges legal, but keeping orange juice illegal.

International Regulations

Cannabis-derived CBD products are illegal on the federal level but are legal under some state laws. Check your state’s laws and those anywhere you travel. And keep in mind that nonprescription CBD products are not FDA approved and may be inaccurately labeled.

Future Legal Trends

Meanwhile, industry groups have requested FDA rules that would allow CBD to be sold legally. In January, the agency rejected the request, indicating that CBD did not meet applicable safety standards under current law. Instead, the FDA advised the creation of a brand-new regulatory pathway that could include safeguards such as a minimum legal purchase age. But creating such a pathway would require an act of Congress — something unlikely to happen soon.

Public Perception and Misconceptions About CBD

Public Perception and Misconceptions About CBD
Public Perception and Misconceptions About CBD

Common Myths and Facts

Despite the growing popularity of CBD, it still carries a stigma rooted in misconceptions and misinformation. One common myth is that CBD can get you high, similar to THC. However, CBD is non-psychoactive and does not produce the euphoric effects associated with THC. Another misconception is that all CBD products are the same, but the quality and concentration can vary significantly between products.

Media Influence on CBD Popularity

The media has played a significant role in shaping public perception of CBD. Positive media coverage has contributed to its popularity, but it has also led to exaggerated claims about its benefits. It’s crucial to rely on scientific evidence rather than media hype when evaluating the efficacy of CBD products.

Public Awareness and Education

Public awareness about CBD has increased, but there is still a lack of comprehensive education on the subject. Many people are unaware of the differences between high-quality CBD and unregulated products. Educational initiatives are needed to provide accurate information and dispel myths surrounding CBD.

Understanding the truth about CBD is essential for making informed decisions. It’s time to break down these barriers and shed light on the truth behind CBD.

Ongoing Research and Future Directions

Current Clinical Trials

Numerous clinical trials are currently being conducted to explore the potential benefits and risks of CBD. These trials aim to provide more concrete evidence on its efficacy for various conditions, including pain management and anxiety. Ongoing research is crucial for validating earlier findings and ensuring the safe use of CBD products.

Areas Needing More Research

While some study findings are available, more research is necessary to draw definitive conclusions. Key areas that require further investigation include the long-term safety of CBD usage and its potential interactions with other medications. This highlights the importance of consulting a qualified healthcare professional before trying CBD.

Potential Future Applications

The future of CBD research looks promising, with potential applications extending beyond current uses. Researchers are exploring its efficacy in treating conditions such as epilepsy, multiple sclerosis, and even certain types of cancer. The ongoing studies aim to unlock new therapeutic potentials for CBD, making it a subject of great interest in the medical community.

Our ongoing research is delving into the untapped potential of hemp and CBD products, uncovering new benefits and applications that could revolutionize wellness. Stay updated with our latest findings and future directions by visiting our website.


In summary, while CBD has garnered significant attention and shows promise in managing conditions such as anxiety, pain, and insomnia, it is essential to approach its use with caution. The current body of research, though encouraging, is still in its infancy, and more rigorous studies are needed to fully understand its benefits and potential risks. Consulting with a qualified healthcare professional before incorporating CBD into your wellness routine is highly recommended. By staying informed and cautious, you can make a more educated decision about whether CBD is a suitable option for you.

Frequently Asked Questions

What is CBD?

CBD, or cannabidiol, is a natural compound found in cannabis plants. Unlike THC, it does not cause a high and is often used for its potential health benefits.

Is CBD legal?

The legality of CBD varies by location. In the United States, CBD derived from hemp is legal under federal law, but state laws may vary. It’s important to check local regulations.

How does CBD work?

CBD interacts with the body’s endocannabinoid system, which helps regulate various functions such as pain, mood, and sleep. It influences the activity of neurotransmitters and may reduce inflammation.

What are the potential benefits of using CBD?

CBD is believed to help with pain management, anxiety reduction, and sleep improvement. However, more research is needed to fully understand its benefits.

Are there any side effects of using CBD?

Common side effects of CBD include nausea, irritability, and sleepiness. It may also interact with certain medications, so it’s important to consult a healthcare professional before using it.

What forms of CBD products are available?

CBD is available in various forms, including oils and tinctures, edibles, and topical applications. Each form has different absorption rates and effects.

How should I determine the right dosage of CBD?

Determining the right dosage of CBD depends on various factors, including your body weight, the condition being treated, and individual tolerance. It’s best to start with a low dose and gradually increase it while consulting a healthcare professional.

Is more research needed on CBD?

Yes, while preliminary studies are promising, more high-quality research is needed to fully understand the potential benefits and risks of CBD use.

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