Don’t Take CBD Before Reading This! Will CBD Make Me Tired?

In recent years, CBD has gained significant attention for its potential health benefits, including pain relief, anxiety reduction, and improved sleep quality. However, one question that often arises is whether CBD can make you tired. This article aims to explore the various factors that influence how CBD affects your energy levels and whether it can indeed cause fatigue.

Table of Contents

Key Takeaways

  • CBD interacts with the endocannabinoid system, which plays a crucial role in maintaining homeostasis in the body.
  • The effects of CBD on energy levels can be dose-dependent, with higher doses more likely to cause drowsiness.
  • CBD cream can potentially make you tired, but its effects vary from person to person.
  • Individual responses to CBD are influenced by genetic factors, lifestyle, and concurrent medications.
  • Starting with a low dose and gradually adjusting can help minimize the risk of experiencing fatigue from CBD.

The Mechanism of CBD and Its Effects on the Human Body

The Mechanism of CBD and Its Effects on the Human Body
The Mechanism of CBD and Its Effects on the Human Body

Cannabidiol (CBD) is a chemical compound found in the cannabis plant, distinct from tetrahydrocannabinol (THC), which is known for its psychoactive effects. CBD does not cause a ‘high’; instead, it appears to have a calming and relaxing effect on the body. People use CBD for various medical issues, including chronic pain, inflammation, anxiety, insomnia, and seizures.

Interaction with the Endocannabinoid System

The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring THC. The ECS plays a crucial role in regulating a range of functions and processes, including sleep, mood, appetite, memory, and reproduction. CBD interacts with the CB1 and CB2 receptors in the ECS, which are found throughout the body. This interaction is believed to contribute to the compound’s therapeutic effects.

Influence on Neurotransmitters

CBD also influences neurotransmitter activity in the brain. It has been shown to affect serotonin receptors, which play a role in mood regulation. Additionally, CBD may inhibit the breakdown of anandamide, an endocannabinoid known as the ‘bliss molecule,’ thereby enhancing its effects. This modulation of neurotransmitter activity can lead to a reduction in anxiety and an improvement in overall mood.

Dose-Dependent Effects

The effects of CBD can vary depending on the dosage. At lower doses, CBD may promote alertness and reduce anxiety, while higher doses may have a sedative effect. This dose-dependent variability is important for users to consider when determining the appropriate amount of CBD for their needs. Your level of absorption and reaction to CBD depends on a variety of factors including your metabolism, biochemistry, and genetics.

The endocannabinoid system is the system in your body that interacts with the active compounds in cannabis, and each person’s operates a little differently.

Understanding the Potential Side Effects of CBD

Common Side Effects

CBD, like any other supplement or medication, can have side effects. Some of the most common side effects include dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue. It is crucial to consult with a healthcare provider before starting CBD, especially if you are taking other medications. This is because CBD can interact with other drugs, potentially altering their effects.

Rare Side Effects

While less common, some individuals may experience more severe side effects such as changes in mood, dizziness, or liver damage. These rare side effects underscore the importance of purchasing CBD from reputable sources that provide transparent lab results to ensure product safety.

Long-Term Implications

The long-term effects of CBD are still being studied. However, there is some evidence to suggest that prolonged use may lead to tolerance, requiring higher doses to achieve the same effects. This is particularly relevant for those using CBD for chronic conditions or cbd for pets. It is advisable to monitor any long-term use closely and consult healthcare providers regularly.

Always ensure that you are using high-quality CBD products and consult with healthcare professionals to mitigate potential risks.

How CBD Dosage Influences Fatigue

Low vs. High Dosage

The dosage of CBD plays a crucial role in determining its effects on the body, including fatigue. Low doses of CBD are often associated with increased alertness and reduced anxiety, while higher doses may lead to sedation and drowsiness. This biphasic effect means that the same compound can have different effects at different concentrations. For instance, a study found that subjects consuming 5 mg/kg of CBD experienced varying levels of fatigue depending on the timing and amount of the dose.

Individual Variability

Individual responses to CBD can vary significantly due to factors such as genetics, metabolism, and overall health. Some people may find that even low doses of CBD make them feel tired, while others may not experience any fatigue at all. This variability underscores the importance of personalized dosing strategies. It is advisable to start with a low dose and gradually increase it to find the optimal level that minimizes fatigue.

Adjusting Dosage to Minimize Fatigue

To minimize the risk of fatigue, it is essential to adjust the dosage carefully. Begin with a small amount and monitor your body’s response. If you experience drowsiness, consider lowering the dose or adjusting the timing of administration. For example, taking CBD in the evening rather than in the morning may help mitigate daytime fatigue. Additionally, combining CBD with other supplements or lifestyle changes can also influence its effects on energy levels.

Fatigue can be short-lived as the body adjusts or may indicate the dosage is too high. The only way to remedy this situation may be to use it before bed, watch medical interactions, consider caffeine intake, and lower the dosage.

CBD Cream and Its Impact on Energy Levels

CBD Cream and Its Impact on Energy Levels
CBD Cream and Its Impact on Energy Levels

Absorption Through the Skin

Cannabidiol cream provides a topical application designed for targeted skin absorption. It is commonly used to treat localized pain. Differences in alertness can occur for the following reasons:

  • CBD interacts with the body’s endocannabinoid system (ECS), maintaining homeostasis. Temporary fatigue can result from an attempt to restore the body to normal following extensive sleep deprivation from pain.
  • Since pain can sap the body of energy, people can feel more invigorated without pain.

Localized vs. Systemic Effects

CBD cream is primarily designed for localized relief, meaning it targets specific areas of the body. This localized application can lead to different effects compared to systemic forms of CBD, such as oils or edibles. Localized application may result in less systemic fatigue because the CBD is not widely distributed throughout the body.

Comparing CBD Cream to Other Forms

When comparing CBD cream to other forms of CBD, such as oils, capsules, or even cbd for horses, it is essential to consider the method of delivery and its impact on energy levels. While systemic forms of CBD can affect the entire body and potentially lead to more pronounced fatigue, topical applications like creams are less likely to cause widespread drowsiness. However, individual responses can vary, and some users may still experience fatigue depending on their unique physiology and dosage.

The Role of Tolerance in CBD-Induced Fatigue

Developing Tolerance Over Time

When individuals begin using CBD, they may experience drowsiness as their bodies adjust. This initial fatigue is often temporary. As tolerance increases, the body becomes accustomed to CBD, potentially reducing some side effects. However, this adaptation may necessitate dosage adjustments to maintain the desired effects.

Managing Tolerance

To manage tolerance effectively, users should consider the following strategies:

  1. Start with a low dose: Gradually increase the dosage to find the optimal balance between efficacy and side effects.
  2. Monitor and adjust: Regularly assess the effects and adjust the dosage as needed.
  3. Consider breaks: Periodic breaks from CBD can help reset tolerance levels.

Implications for Long-Term Use

Long-term use of CBD, including CBD topicals, requires careful management of tolerance. As tolerance builds, users may need higher doses to achieve the same effects, which could lead to increased costs and potential side effects. Therefore, understanding and managing tolerance is crucial for sustainable and effective CBD use.

Fatigue can be short-lived as the body adjusts to CBD, but long-term management of tolerance is essential to minimize side effects and maintain efficacy.

Comparing CBD to Other Cannabinoids in Terms of Fatigue


When comparing CBD to THC, the primary psychoactive component of cannabis, it is essential to note that THC is more likely to induce drowsiness. While CBD is often used for its calming effects, it does not typically produce the same level of sedation as THC. This distinction is crucial for individuals seeking the therapeutic benefits of cannabinoids without the unwanted side effect of fatigue.

The Entourage Effect

The entourage effect refers to the synergistic interaction between various cannabinoids and terpenes found in the cannabis plant. This phenomenon suggests that the combined effect of these compounds can enhance the therapeutic benefits while potentially mitigating adverse effects such as fatigue. For instance, products like CBD gummies that contain a full spectrum of cannabinoids may offer a balanced experience, reducing the likelihood of drowsiness.

Non-Drowsy Cannabinoid Options

For those concerned about fatigue, there are non-drowsy cannabinoid options available. Cannabigerol (CBG) is one such cannabinoid that has shown promise in providing therapeutic benefits without causing drowsiness. Additionally, products that blend CBD with natural stimulants can offer an alternative for those looking to avoid the sedative effects commonly associated with cannabinoids.

Understanding the differences between various cannabinoids and their effects on fatigue can help individuals make informed decisions about their use. By selecting the appropriate cannabinoid and dosage, it is possible to enjoy the benefits without experiencing unwanted drowsiness.

CBD and Sleep: A Complex Relationship

CBD and Sleep A Complex Relationship
CBD and Sleep A Complex Relationship

CBD’s Role in Sleep Regulation

CBD interacts with the endocannabinoid system (ECS), a network of neurotransmitters and receptors found throughout the body. This interaction can help promote a sense of calm and relaxation, which may be beneficial for sleep. However, the exact mechanisms by which CBD influences sleep are still not fully understood and require further research.

Impact on Sleep Quality

CBD has been reported to help some individuals stay asleep longer and improve overall sleep quality. For instance, some users have noted that CBD helps them turn off racing thoughts, allowing them to drop into deep sleep quicker. However, these effects can be highly individual and may vary from person to person.

Timing of CBD Administration for Sleep

The timing of CBD administration can significantly impact its effectiveness for sleep. Some people find that taking CBD tinctures in the evening helps them relax and prepare for bed, while others may experience a rebound effect that disrupts their sleep cycle. It is essential to experiment with timing to find what works best for you.

While CBD is not endorsed by any medical body for sleep, it has shown promise in helping some individuals achieve better sleep. Always consult with a healthcare provider before starting any new supplement, especially if you have existing health conditions or are taking other medications.

Factors Influencing Individual Responses to CBD

Your level of absorption and reaction to CBD depends on a variety of factors including your genetics. The endocannabinoid system in your body interacts with the active compounds in cannabis, and each person’s system operates a little differently. Investigating how genetic and clinical factors influence individual responses to CBD treatment is vital. For instance, a genetic mutation present in 20% of Americans makes them naturally produce more endocannabinoids, which might result in lower levels of anxiety but also a reduced response to CBD.

CBD users do not experience the same results universally, as lifestyle and diet play significant roles. Research on both animal and human subjects in stressful situations found that those on CBD showed fewer signs of nervousness. Factors such as metabolism and biochemistry can influence how CBD is absorbed and utilized in the body. For example, a high-fat diet may increase the absorption rate of CBD, leading to more pronounced effects.

The effects of sublingual (under the tongue) or orally consumed CBD vary depending on the individual and dosage, but most people feel a sense of relaxation, calmness, reduced anxiety, and/or full-body pain relief. However, concurrent medications can significantly alter these effects. CBD interacts with the CB1 and CB2 receptors, which play a role in a wide range of bodily functions. Therefore, it is crucial to consult with a healthcare provider to understand potential interactions with other medications you may be taking.

Building up a tolerance to CBD is possible, similar to many other drugs and chemicals. If you find that it’s not working as well after a while, try taking a few days’ break to reset your system before starting with a low dose again.

Practical Tips for Using CBD Without Experiencing Fatigue

Starting with a Low Dose

When beginning CBD usage, it is advisable to start with a low dose. This approach allows the body to gradually adjust to the compound, potentially minimizing initial side effects such as fatigue. By starting low, users can monitor their body’s response and incrementally increase the dosage if needed.

Monitoring and Adjusting Dosage

Regularly monitoring the effects of CBD is crucial. If fatigue is experienced, it may be necessary to adjust the dosage. Keeping a journal of CBD intake and its effects can be beneficial. This practice helps in identifying patterns and making informed decisions about dosage adjustments.

Combining CBD with Other Supplements

Combining CBD with other supplements can also influence its effects. For instance, pairing CBD with caffeine may counteract any drowsiness. However, it is essential to consider potential medical interactions and consult with a healthcare provider before combining supplements.

Fatigue can be short-lived as the body adjusts or may indicate the dosage is too high. The only way to remedy this situation may be to use it before bed, watch medical interactions, consider caffeine intake, and lower the dosage.

Scientific Research on CBD and Fatigue

Scientific Research on CBD and Fatigue
Scientific Research on CBD and Fatigue

Current Studies

Recent studies have explored the relationship between CBD and fatigue, focusing on various factors such as dosage, administration methods, and individual responses. Current research indicates that while CBD can induce fatigue in some individuals, the effects are often dose-dependent and vary widely among users. Researchers are particularly interested in how CBD interacts with the endocannabinoid system to influence energy levels and overall fatigue.

Gaps in Research

Despite the growing body of research, there are still significant gaps in our understanding of how CBD affects fatigue. Many studies have small sample sizes or lack long-term data, making it difficult to draw definitive conclusions. Additionally, the variability in individual responses to CBD complicates the ability to generalize findings. More comprehensive studies are needed to fully understand the mechanisms behind CBD-induced fatigue.

Future Directions

Future research should aim to address these gaps by conducting larger, long-term studies that consider a variety of factors, including genetic predispositions and lifestyle choices. Researchers should also explore the potential for CBD to interact with other medications, as this could significantly impact its effects on fatigue. By addressing these areas, we can develop a more nuanced understanding of how CBD influences fatigue and how to mitigate its potential side effects.

Scientific research on CBD and fatigue has shown promising results, indicating that CBD may help alleviate symptoms of fatigue and improve overall energy levels. To learn more about the latest findings and how CBD can benefit you, visit our website today!


In conclusion, the effects of CBD, particularly in the form of creams, on inducing tiredness are multifaceted and vary from person to person. While some individuals may experience drowsiness, others might find themselves more alert and focused. The potential for CBD to make you tired depends on several factors, including dosage, individual body composition, and tolerance levels. It is crucial to monitor your body’s response to CBD and adjust the dosage accordingly. If drowsiness is a concern, consider using CBD products before bedtime or exploring non-drowsy alternatives. Always consult with a healthcare professional to ensure that CBD is a suitable option for your specific needs.

Frequently Asked Questions

Can CBD cream make you tired?

Yes, there is a potential for CBD cream to make you tired. The effects can vary from short-term to long-term, and it is important to gauge how it affects you personally.

What are the chances of CBD cream making me tired?

Fatigue is a common side effect of CBD cream. It slows down the breakdown of anadamide, making people feel more relaxed and potentially improving sleep quality.

Will CBD make me feel drowsy?

Drowsiness is not the most common result of using CBD. Some people may feel more alert and focused, while others may feel relaxed. If you feel drowsy, you might need to lower your dosage.

How long does it take for the effects of CBD to be felt?

The time it takes for CBD effects to be felt can vary. Some people might feel the effects within minutes, while for others it might take longer. It also depends on the form of CBD used.

Can increasing my tolerance to CBD reduce drowsiness?

Yes, as your body adjusts to CBD, you may experience less drowsiness. However, as tolerance increases, you might need to adjust your dosage to experience the same effects.

What are some non-drowsy forms of CBD?

There are various forms of CBD that may not cause drowsiness, such as lower doses of CBD oil or CBD products specifically formulated to avoid drowsiness. Always consult with a healthcare provider for personalized advice.

Can CBD help with sleep regulation?

Yes, CBD can help with sleep regulation by reducing anxiety and stress, which are common barriers to good sleep. However, its effects can vary depending on the individual.

Is it better to take CBD in the morning or evening to avoid fatigue?

If CBD makes you drowsy, it is better to take it in the evening, about an hour or two before bed. However, some people find it useful to take it in the morning and evening to promote a sense of calm throughout the day.

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